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Publication
Publications (primary)
Lim J*, Lin EV*, Hong JY*†, Vaidyanathan B, E0rickson SA, Annicelli C, Medzhitov R†. “Induction of natural IgE by glucocorticoids”, J Exp Med, 219(10):e20220903 (2022). https://doi.org/10.1084/jem.20220903
- Selected as one of the top 10 papers in 2022: The Year in Experimental Medicine
Hwang SS*, Lim J*, Yu Z, Kong P, Sefik E, Xu H, Harman CCD, Kim LK, Lee KR, Li HB, Flavell RA. “mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence”, Science, 367(6483):1255-1260 (2020). https://doi.org/10.1126/science.aax0194.
Lim J*, Kim D*, Lee Y-S*, Ha M, Lee M, Yeo J, Chang H, Song J, Ahn K, Kim VN. “Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation”, Science, 361(6403):701-704 (2018). https://doi.org/10.1126/science.aam5794
Lim J*, Lee M*, Son A, Chang H, Kim VN. “mTAIL-seq reveals dynamic poly(A) tail regulation in oocyte-to-embryo development”, Genes Dev, 30(14):1671-82 (2016). https://doi.org/10.1101/gad.284802.116
Lim J*, Ha M*, Chang H*, Kwon SC, Simanshu DK, Patel DJ, Kim VN. “Uridylation by TUT4 and TUT7 marks mRNA for degradation”, Cell, 159(6):1365-76 (2014). https://doi.org/10.1016/j.cell.2014.10.055
- Research highlight by Nature Chemical Biology
Chang H*, Lim J*, Ha M, Kim VN. “TAIL-seq: genome-wide determination of poly(A) tail length and 3' end modifications”, Mol Cell, 53(6):1044-52 (2014) (Cover article). https://doi.org/10.1016/j.molcel.2014.02.007
- Selected as the cover article
- Spotlight by Trends in Biochemical Sciences
Publications (co-author)
Park J*, Kim M*, Yi H*, Baeg K*, Choi Y, Lee YS, Lim J, Kim VN. "Short poly(A) tails are protected from deadenylation by the LARP1-PABP complex", Nat Struct Mol Biol. Mar;30(3):330-338 (2023).
Hsu JC, Laurent-Rolle M, Pawlak JB, Xia H, Kunte A, Hee JS, Lim J, Harris LD, Wood JW, Evans GB, Shi PY, Grove TL, Almo SC, Cresswell P. “Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication”, Mol Cell, 82(9):1631-1642.e6 (2022).
Jeong J†, Shin JH, Li W, Hong JY, Lim J, Hwang JY, Chung JJ, Yan Q, Liu Y, Choi J, Wysolmerski J. “MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells”, Cell Rep, 37(13):110160 (2021).
Shin JH†, Jeong J, Maher SE, Lee H, Lim J, Bothwell ALM†. “Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis", Proc Natl Acad Sci U S A, 118(48):e2110241118 (2021).
Sullivan ZA, Khoury-Hanold W, Lim J, Smillie C, Biton M, Reis B, Zwick RK, Pope SD, Israni-Winger K, Parsa R, Philip NH, Rashed S, Palm N, Wang A, Mucida D, Regev A, Medzhitov R. “γδ T cells regulate the intestinal response to nutrient sensing”, Science, 371(6535):eaba8310 (2021).
Shin JH, Jeong J, Choi J, Lim J, Dinesh RK, Braverman J, Hong JY, Maher SE, Amezcua Vesely MC, Kim W, Koo JH, Tang W, Wu D, Blackburn HN, Xicola RM, Llor X, Yilmaz O, Choi JM, Bothwell ALM. “Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1”, iScience, 24(5):102411 (2021).
Hong JY, Lim J, Carvalho F, Cho JY, Vaidyanathan B, Yu S, Annicelli C, Ip WKE, Medzhitov R. “Long-term programming of CD8 T cell immunity by perinatal exposure to glucocorticoid”, Cell, 180(5):847-861.e15 (2020).
Ye J, Bian X, Lim J, Medzhitov R. “Adiponectin and related C1q/TNF-related proteins bind selectively to anionic phospholipids and sphingolipids”, Proc Natl Acad Sci U S A, 117(29):17381-17388 (2020).
Kim D*, Lee Y-S*, Jung SJ*, Yeo J*, Seo J, Lee YY, Lim J, Chang H, Song J, Yang J, Kim JS, Jung G, Ahn K, Kim VN. “Viral hijacking of the TENT4-ZCCHC14 complex protects viral RNAs via mixed tailing”, Nat Struct Mol Biol, 27(6):581-588 (2020).
Yi H*, Park J*, Ha M, Lim J, Chang H, Kim VN. “PABP Cooperates with the CCR4-NOT Complex to Promote mRNA Deadenylation and Block Precocious Decay”, Mol Cell, 70(6):1081-1088.e5 (2018).
Chang H*, Yeo J*, Kim JG, Kim H, Lim J, Lee M, Kim HH, Ohk J, Jeon HY, Lee H, Jung H, Kim KW, Kim VN. “Terminal Uridylyltransferases Execute Programmed Clearance of Maternal Transcriptome in Vertebrate Embryos”, Mol Cell, 70(1):72-82.e7 (2018).
Lee M, Choi Y, Kim K, Jin H, Lim J, Nguyen TA, Yang J, Jeong M, Giraldez AJ, Yang H, Patel DJ, Kim VN. “Adenylation of maternally inherited microRNAs by Wispy”, Mol Cell, 56(5):696-707 (2014).
Heo I*, Ha M*, Lim J, Yoon MJ, Park JE, Kwon SC, Chang H, Kim VN. “Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs”, Cell, 151(3):521-32 (2012).